Volume 5, Issue 4, July 2017, Page: 68-72
Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn
Zafar Iqbal, Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Zhang Hai, School of Chemistry and Chemical Engineering, Qianbei Featured Resources, Applied Research Key Laboratory, Zunyi Normal College, Guizhou, Zunyi, China
Hong Yan Ping, Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engineering, Jiangxi, Agriculutural University, Nanchang, China
Abdul Ghaffar, Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan
Munaza Mumtaz, Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan
Luban Liaqat, Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Received: Mar. 7, 2017;       Accepted: Mar. 27, 2017;       Published: Oct. 30, 2017
DOI: 10.11648/j.plant.20170504.12      View  1902      Downloads  119
Abstract
Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.
Keywords
Glycyrrhiza Glabra Linn, Orgnic Extracts, Antioxidant, Antibacterials
To cite this article
Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, Luban Liaqat, Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn, Plant. Vol. 5, No. 4, 2017, pp. 68-72. doi: 10.11648/j.plant.20170504.12
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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