Volume 6, Issue 3, September 2018, Page: 53-59
Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review
Lengbiye Moke, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Gédéon Bongo, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Kongumbeti Goga, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Jeff Iteku, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Inkoto Liyongo, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Claudine Tshiama, Teaching and Administration in Nursing Care, Higher Institute of Medical Techniques, Kinshasa, Democratic Republic of the Congo
Ngunde Ngunde, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Koto-te-Nyiwa Ngbolua, Department of Biology, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Pius Mpiana, Department of Chemistry, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Received: Jun. 9, 2018;       Accepted: Sep. 30, 2018;       Published: Oct. 29, 2018
DOI: 10.11648/j.plant.20180603.11      View  130      Downloads  4
Abstract
The aim of this review was to provide an updated knowledge on the Phytochemistry and Pharmacognosy of Isolona hexaloba Engl. & Diels. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Isolona hexaloba from various electronic databases (PubMed Central, PubMed, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the Isolona hexaloba and Isolona genus naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package. The findings revealed that this plant is traditionally used as a purgative and in treating sores, smoke from the bark as a strained muscle relaxant, infectious and parasitic pathologies, loss of appetite, rheumatism, intestinal cramps, headache, back pains, sexual weakness. This plant is reported to possess various biological properties like antioxidant, antimicrobial, antihyperglycemic, antileishmanial and antimalarial. These properties are due to the presence of numerous naturally occurring phytochemicals like flavonoids, alkaloids, tannins, saponins, reducting sugars, coumarins, terpenes and steroids. The present mini-review revealed that Isolona hexaloba Engl. & Diels is a good candidate for Tropical Plants Screening Research program for the development of lead compounds against genetic and parasitic diseases such as the evaluation of the anthelminthic activity.
Keywords
Isolona hexaloba, Phytochemistry, Pharmacognosy, Anthelminthic Activity
To cite this article
Lengbiye Moke, Gédéon Bongo, Kongumbeti Goga, Jeff Iteku, Inkoto Liyongo, Claudine Tshiama, Ngunde Ngunde, Koto-te-Nyiwa Ngbolua, Pius Mpiana, Isolona hexaloba Engl. & Diels: Phytochemistry, Pharmacology and Future Directions: A Mini-Review, Plant. Vol. 6, No. 3, 2018, pp. 53-59. doi: 10.11648/j.plant.20180603.11
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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